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KMID : 0374019960190030359
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Ewha Medical Journal
1996 Volume.19 No. 3 p.359 ~ p.364
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The Clinical Efficacy of Levofloxacin(CRAVIT) in the Treatment of Cutaneous Infection
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강호정
김현주/서승리/김영숙/이미애/함정희
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Abstract
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Background:
@EN Levofloxacin, an oral fluroquinolone antibacterial agent, is the optical S-(-)isomer of
ofloxacin. In vitro it is generally twice as potent as ofloxacin and active against most aerobic
gram positive and gram negative organisms, but only moderate activities against anaerobics.
@ES Objectives:
@EN Our purpose was to investigate the therapeutic efficacy and tolerability of levofloxacin
in patients with several kinds of cutaneous infections.
@ES Method:
@EN Levofloxacin (CRAVIT ; Korea Daiich Parm. Co) 300-600mg/day for 5-14 davs was
administrated to eighteen patients with cutaneous and subcutaneous infections. The Bacterial
culture and laboratory tests were performed prior to and after treatments. Clinical effects and
adverse events were evaluated on laboratory indices.
@ES Results:
@EN 1) Nine of thirteen case (70%) were useful, four cases (30%) were slightly useful.
2) Clinically twelve of eighteen cases were cured and eight cases were partial response to the
drug.
3) there were no laboratory abnormalities after levofloxacin treatment
4) Side effects were not significant except dizziness and sleep disturbance.
@ES Conclusion:
@EN Levofloxacin was evaluated as a highly effective antibacterial agent against dermatologic
infections.
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KEYWORD
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